Table 1.

Functional connectivity [human–human] > [human–computer].

Analysis	Coordinates∗	Peak voxels t-value (degrees of freedom)	P	Anatomical regions in cluster	BA	Probability	n of voxels
PPI with angular gyrus	(–64, -10, 32)	3.16 (25)	0.002	Subcentral area	43	0.45	251
(±57, -70, 26) as seed				Primary somatosensory cortex	1, 2	0.28
	(–30, 22, 40)	2.97 (25)	0.003	Dorsolateral prefrontal cortex	9	1.00	324
	(–26, 44, 22)	2.72 (25)	0.006	Dorsolateral prefrontal cortex	46	1.00	39
	(–34, 48, 24)	2.60 (25)	0.008	Dorsolateral prefrontal cortex	46	0.82	10
				Pars triangularis Broca’s area	45	0.18
	(6, 48, 36)	2.58 (25)	0.008	Dorsolateral prefrontal cortex	9	1.00	8

Functional connectivity increases determined by psychophysiological interaction (PPI) analysis in the human–human condition relative to the human–computer condition are shown for the anatomically defined AG seed. Areas included in the functional networks are identified by MNI coordinates, levels of statistical significance (t-value and P), regions included in the cluster including Brodmann’s Area (BA), estimated probability, and n of voxels, which is a measure of cluster volume.

^∗Coordinates are based on the MNI system and (-) indicates left hemisphere. Seed centroids are based on channel groups for which coordinates from right and left hemisphere clusters have been averaged. Averages account for minor inter-individual variations in channel numbers for each group. Probability refers to the probability of a certain cluster corresponding to the listed neural structure as evaluated by the MNI atlas.