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. 2017 Nov 27;7:16406. doi: 10.1038/s41598-017-16618-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Immunohistochemical analysis of Naglu-Neo and Hsd17b1-LacZ/Neo male mice. Immunohistochemical staining for LAMP1 was used to demonstrate lysosomes in the Hsd17b1-LacZ/Neo mice. Increased staining was observed in the kidney (B), liver (D) and epididymis (H) compared to the WT (A,C and G), while no difference in the intensity of staining was shown in testis sections from the WT and Hsd17b1-LacZ/Neo mice (E and F).