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. 2017 Nov 23;8:946. doi: 10.3389/fphys.2017.00946

Figure 2.

Figure 2

Effects of individual vs. combined block of K+-currents by acacetin (3.2 μM) on the human atrial AP in normal and cAF-remodeled myocytes paced at 1 Hz. (A,B) Effects on the atrial AP in (A) normal and (B) cAF-remodeled myocytes; a zoomed-in view for the traces of AP during phase-3 is plotted to the right. (C,D) Alterations in the (i) APD90 and (ii) APD30 by the simulated block obtained from atrial cells in (C) normal and (D) cAF-remodeled myocytes.