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Simulated activation-recovery intervals (ARI) (A), Vmax (B), and CV (conduction velocity) (C) measured in 1D cAF-remodeled atrial strand models as a function of BCL for control (drug-free), individual and combined Na+- and (i) IKur block and (ii) action of acacetin. ARI values were measured as the interval between the time at which the AP depolarizes to −20 mV and the time it reaches a 90% repolarization.
