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. 2017 Nov 23;8:315. doi: 10.3389/fendo.2017.00315

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Copyright © 2017 Bayer and Fraker.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The two major pathways in the cellular folate cycle. (A) It details the purinosome, DNA synthesis, cellular energy pathway (ATP synthesis), and immune system modulation. (B) It details amino acid synthesis (homocysteine–methionine).