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. 2017 Nov 23;8:315. doi: 10.3389/fendo.2017.00315

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Copyright © 2017 Bayer and Fraker.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Differences in natural killer (NK) effector cell population expressed as % of total lymphocytes in 26 control subjects, 12 long-standing type 1 diabetes (T1D) patients and 7 multiple autoantibody positive at-risk subjects. (B) Randomized age/sex-matching sub-analysis between control subjects and long-standing T1D patients. No correlation was found between NK effector population and either age or sex. Peripheral blood samples from the subjects in this study were obtained after obtaining written informed consent. The study was reviewed and approved by the University of Miami Institutional review Board (protocol 1995-0119).