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. 2017 Nov 23;8:315. doi: 10.3389/fendo.2017.00315

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Copyright © 2017 Bayer and Fraker.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Insulin-stimulated glucose uptake of L6 myotubular cells exposed to sequential dosing of folic acid (n = 4). Insulin-stimulated glucose uptake was significantly different from basal uptake in all doses of folic acid (lowest dose 2.2 μM present in media) except 25 and 50 μM. Differential uptake decreased in a dose-dependent fashion.