TABLE 4.
Modal MICs and categorical interpretation for meropenem, ceftolozane-tazobactam, and ceftazidime-avibactam against the 2 P. aeruginosa isolates used in the study
| P. aeruginosa isolate | Antibiotic MIC (μg/ml) (interpretation)a |
||
|---|---|---|---|
| Meropenem | Ceftolozane-tazobactam | Ceftazidime-avibactam | |
| ATCC 27853 | 0.5 (S) | 0.5/4 (S) | 2/4 (S) |
| 147 | 8 (R) | 4/4 (S) | 8/4 (S) |
a
The breakpoints for meropenem are 2, 4, and 8 μg/ml for susceptible (S), intermediate, and resistant (R) strains, respectively; the breakpoints for ceftolozane-tazobactam are 4, 8, and 16 μg/ml for susceptible, intermediate, and resistant strains, respectively (ceftolozane component); and the breakpoints for ceftazidime-avibactam are 8 and 16 μg/ml for susceptible and resistant strains, respectively (ceftazidime component).