Table 2.
Main characteristics of two groups of the asthma cohort dichotomized according to the severity of distress disorder indicated by the SGRQ's Impacts score.
| Parameters | Lower impacts score | Higher impacts score | p |
|---|---|---|---|
| Age (years) | 40.5 (28.5–59.5) | 52 (43–57) | 0.003 |
| Smoking (pack-years) | 0 (0–0.5) | 0 (0–5) | 0.03 |
| Dyslipidemia present (n/y) | 67/17 | 51/32 | 0.009 |
| Hypertension present (n/y) | 62/22 | 42/41 | 0.002 |
| Height (m) | 1.70 ± 0.10 | 1.66 ± 0.10 | 0.003 |
| Irisin (ng/mL) | 8.187 (7.402–9.312) | 7.666 (6.838–8.54) | 0.02 |
| Triglyceride (mmol/L) | 1.2 (0.9–1.8) | 1.6 (1–2) | 0.04 |
| Fibrinogen (g/L) | 3.18 ± 0.62 | 3.49 ± 0.62 | 0.001 |
| FVC % pred | 95.33 ± 13.59 | 90.05 ± 13.58 | 0.02 |
| FEV1 % pred | 90.27 ± 13.86 | 82.33 ± 15.20 | <0.001 |
| FEF25-75 % pred | 72.56 ± 22.06 | 61.11 ± 21.05 | 0.001 |
| RV % pred | 129 (112–146) | 139 (124−169) | 0.01 |
| RV/TLC % pred | 117.60 ± 19.11 | 129.46 ± 19.32 | <0.001 |
| Raw current | 0.2 (0.17–0.25) | 0.24 (0.19–0.32) | 0.003 |
| Symptom score | 15.43 (8.40–26.87) | 50.46 (31.44–66.22) | <0.001 |
| Activity score | 29.38 (11.56–42.82) | 59.45 (47.68–66.95) | <0.001 |
| Total score | 17.10 (9.22–25.57) | 47.11 (37.88–56.10) | <0.001 |
The lower (n = 84) and higher (n = 83) Impacts score group had Impacts score <22.53 or ≥22.53, respectively. Only parameters with significant difference are indicated. Comparison of smoking (in years), presence or absence of diabetes, myocardial infarct, stroke, and steroid use in case history, RR systolic (mmHg), RR diastolic (mmHg), disease duration (years), waist (cm), weight (kg), BDNF (ng/mL), urea (mmol/L), creatinine (μmol/L), GFR (mL/min/1.73 m2), GOT (U/L), GPT (U/L), γGT (U/L), CK (U/L), LDH (U/L), glucose (mmol/L), insulin (mU/L), HgA1c (%), HOMA index, cholesterol (mmol/L), LDL-C (mmol/L), HDL-C (mmol/L), CRP (mg/L), CRP kat (low/high), procalcitonin (μg/L), sTSH (mU/L) showed no significant difference between the two groups. Data are presented as mean ± SD or median (interquartile range), unless otherwise stated. Differences between the two groups were considered significant at p < 0.05, clinically significant difference between component scores are indicated in bold.