Fig. 3.

uc.339 increases NSCLC growth in an in vivo xenograft murine model. a Tumor volume growth curve in 14 nude mice injected subcutaneously with A549 LV-E (n = 7) or A549 LV-uc.339 (n = 7) and measured from day 8 from the injection until day 29, every 3 days. Data are presented as the mean tumor volumes + s.d. for each animal group. *P < 0.05. **P < 0.01. b qRT-PCR for uc.339 in ex vivo xenografts from the same mice of experiment (a). The expression of uc.339 has been normalized to RNU44 and data are presented as mean ± s.d. of experiments conducted in triplicate per each mouse, normalized to A549 LV-EV. *P < 0.05. c Images of the 14 excised tumors from the mice of experiments (a, b). Scale bar = 1 cm