Table 1.
Characteristics | No. of patients |
Levels of CHI3L1 |
||
Low | High | P value | ||
All | 150 | 97 | 53 | |
Age | 0.009 | |||
Median | 60 | |||
Range | 30-96 | |||
< 60 | 81 | 60 | 21 | |
≥ 60 | 69 | 37 | 32 | |
Sex | 0.713 | |||
Male | 113 | 74 | 39 | |
Female | 37 | 23 | 14 | |
Smoking status | 0.514 | |||
Smoker | 99 | 66 | 33 | |
Non-smoker | 49 | 30 | 19 | |
Alcohol intake | 0.984 | |||
Yes | 56 | 36 | 20 | |
No | 90 | 58 | 32 | |
Grade | 0.736 | |||
Grade 1 | 24 | 16 | 8 | |
Grade 2 | 57 | 36 | 21 | |
Grade 3 | 41 | 29 | 12 | |
T status | 0.886 | |||
pT 1/2 | 31 | 21 | 10 | |
pT 3/4 | 113 | 75 | 38 | |
N status | 0.154 | |||
pN 0 | 63 | 46 | 17 | |
pN 1/2/3 | 81 | 50 | 31 | |
M status | 0.156 | |||
pM 0 | 112 | 78 | 34 | |
pM 1 | 32 | 18 | 14 | |
Stage | 0.712 | |||
I–II | 51 | 35 | 16 | |
III-IV | 93 | 61 | 32 | |
SCCA | 0.539 | |||
≤ 1.5 | 101 | 67 | 34 | |
> 1.5 | 49 | 30 | 19 | |
CEA | 0.389 | |||
≤ 5.0 | 132 | 87 | 45 | |
> 5.0 | 18 | 10 | 8 | |
Treatment | 0.138 | |||
Surgery | 73 | 49 | 24 | |
Chemoradiotherapy | 57 | 37 | 20 | |
Chemotherapy | 11 | 4 | 7 |
CHI3L1: Chitinase 3-like 1; SCCA: Squamous cell carcinoma antigen; CEA: Carcinoembryonic antigen.