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. 2017 Nov 27;7:16343. doi: 10.1038/s41598-017-16109-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Frontal ectopic neuroblast migration after stroke. (A) Regions analyzed from the SVZ toward the infarct (Z1, Z2, Z3). DCX⁺ volume in (B) Z1, (C) Z2 and (D) Z3. (E) Representative neuroblast migration images in MCAO and sham animals at 28d after stroke (scale bar: 100 µm). Naïve group was represented in figure as t = 0. No differences were observed when naïve and sham animals were compared. Data are presented as mean +/− SEM and compared by non-parametric 2-way ANOVA followed by Bonferroni post-hoc testing (Z2: F(1,14) = 2.94, ^#p = 0.0246, Ipsi MCAO vs. Contra MCAO; F(1,14) = 36.08, &p < 0.0001, MCAO vs. Sham; Z3: F(1,14) = 4.96, ^#p = 0.0429 Ipsi MCAO vs. Contra MCAO; F(1,14) = 11.15, ^&p = 0.0049 MCAO vs. Sham) and non-parametric 1-way ANOVA followed by Dunnett post-hoc testing (Z3: *p = 0.0099 MCAO vs. Naïve).