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Structure comparison of HBV and BNC. HBV envelope is composed of a lipid bilayer and three types of envelope proteins (S, M, and L). HBV virion contains core proteins, DNA genome, DNA polymerase, and protein X (right). BNC is a hollow nanoparticle produced by yeast cells. BNC is composed of a lipid bilayer derived from the yeast endoplasmic reticulum and HBV envelope L proteins.
