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. 2017 Nov 12;7(11):150. doi: 10.3390/brainsci7110150

Table 1.

Studies on digital platforms used in the assessment, monitoring and management of BPD.

Study Design Sample Size Sample Characteristics Main Findings
MONARCA [11] Prospective observational study 17 67.1% (n = 45) females
18–60 years (Median age 29.83 years)
Subjective and objective measures in MONARCA correlate well with the HDRS-17 used by clinicians in monitoring BPD
SIMBA [12] Prospective observational study 13 61.5% (n = 8) females
Mean age 47.2 years
High self-reported mood correlates negatively with depressive symptoms
Distance travelled correlates negatively with mania
No. of calls made correlates positively with manic symptoms
No. of text messages sent correlates negatively with depressive symptoms
Mobile Mood Diary [13] Observational study 9 55% (n = 11) females
Mean age 13.6 years
Improved adherence to medications
SIMPLe [14] RCT Ongoing 18–65 years (Mean age) Ongoing
Moodswings.net.au [15] RCT 156 73% (n = 97) females
Median age 39.87 years
Reduction in mood symptoms, improved functioning and improved QoL and medication adherence in intervention group
ORBIT [16] RCT 26 75% females
Median age 46.6 years
Statistically significant improvement in QoL in intervention group t(15) = 2.88, 95% CI: 0.89–5.98, p = 0.011
ERPOnline [17] RCT 96 61.4% females
Median age 43 years
ERPonline increased the frequency of monitoring early signs of mood change. Improved medication adherence at 12 and 48 weeks.
Living with Bipolar [18] RCT 122 72% (n = 88) females
18–65 years (Mean age 43 years)
Improvement in psychological and physical domains of QoL, well-being in the intervention group compared to control
Beating Bipolar [19] RCT 50 38% (n = 19) males
Mean age 43 years
Improvement within the psychological subsection of the WHOQOL-BREF for the intervention group relative to the control group
BIPED [20] RCT 100 Ongoing Ongoing
FiSTAR [21] RCT 25 Ongoing Ongoing
FIMM [22] RCT 19 68.4% (n = 13) females
Mean age
37.2 years
Patients reported stable moods on the QIDS and ASRM over a 120-day period, and on average responded to 81% of the daily message prompts and 88% of the weekly QIDS and ASRM prompts.

MONARCA, MONitoring, treAtment and pRediCtion of bipolAr Disorder Episodes; ERP, Enhanced Relapse Prevention for Bipolar disorder; RCT, randomised controlled trial; WHOQOL-BREF, Brief World Health Organization Quality of Life; BIPED, The Bipolar Interactive Psychoeducation; FI-STAR, The Future Internet Social and Technological Alignment Research; FIMM, Facilitated Integrated Mood Management.