Table 1.
Protein biomarkers of lung cancer defined using proteomic studies.
| Lung Cancer Type | Protein Biomarkers of Lung Cancer | Reference |
|---|---|---|
| NSCLC, SCLC | AGER, C10orf116, ADD2, PRX, LAMB3, SYNM, SPTA1, ANK1, HBE1, HBG1, CA1, TNXB, MMRN2, HBA1, CAV1, HBB, COL6A6, C1orf198, CLIC2, SDPR, EHD2, APOA2, NDUFB7, PRKCDBP, LAMA3, LBN | [33,34,35] |
| ACT, 3 IGFBP3, L-PGDS | [35] | |
| SAA | [36] | |
| SAA, HAP, HGF | [36,37] | |
| TTR | [38,39] | |
| SAA, AAG1/2, CLU, SSA, AAG1, SAA, TTR | [6,35,37,40,41] | |
| APOA4, FIBA, LBN, SAA, CP, HP, TTR, KRT2A, GLT1B, CK1, AKT, MBL2, AAG1-2, FGA | [42] | |
| GSN, HP, FCN3, CNDP1 | [43] | |
| Lung adenocarcinoma | CALCA, CPS1, CHGB, IVL, AGR2, NASP, PFKP, THBS2, TXNDC17, PCSK1, CRABP2, ACBD3, DSG2, LRBA, STRAP, VGF, NOP2, LCN2, CKMT1B, AKR1B10, PCNA, CPD, PSME3, VIL1 | [44,45,46,47] |
| Squamous lung cancer | SERPINB5, RPL5, PKP1, RPL10, AKR1B10, AKR1C1, PCNA, RPS2, AKR1C3, THBS2, ACBD3, VSNL1, AHCY, IMMP10, PAK2, IVL, IARS, PSMD2, GBP5, MCM6, NDRG1, NOP58, S100A2, NRG1-2, CNDP1 | [45,47] |
| UCRP, CER, UPA, MT1-MMP, SFN, TF, ALB, S100A9, STMN, ENO, PLAU, IGFBP7, MMP14, THBS1, TTR | [48] |
NSCLC: non-small-cell lung carcinoma; SCLC: small-cell lung carcinoma.