Table 2. Association of two polymorphisms in UQCRB gene.
|
Clinical (TNM) stage |
||||||
|---|---|---|---|---|---|---|
| II | III | IV | ||||
| SNP | Tissue case | Genotype | No. | Total no. (%) | ||
| rs7836698 | CRC tissues | CC | 3 | 2 | 1 | 6 (40) |
| CT | 1 | 3 | 4 (26.6) | |||
| TT | 2 | 3 | 5 (33.3) | |||
| Non-tumor tissues | CC | 5 | 7 | 1 | 13 (86.6) | |
| CT | 1 | 1 (6.6) | ||||
| TT | 1 | 1 (6.6) | ||||
| rs10504961 | CRC tissues | CC | 4 | 4 | 1 | 9 (60) |
| CT | 1 | 3 | 4 (26.6) | |||
| TT | 1 | 1 | 2 (13.3) | |||
| Non-tumor tissues | CC | 4 | 4 | 1 | 9 (60) | |
| CT | 1 | 4 | 5 (33.3) | |||
| TT | 1 | 1 (6.6) | ||||
Abbreviations: CRC, colorectal cancer; TNM, tumor-node metastasis.
Major/minor allele and location of two SNPs (rs7836698 and rs10504961) were C/T and 5′-UTR, respectively.