Table 1. Genes differentially expressed in ITGA11-KD cells compared with control cells characterized in the Human Fibrosis PCR Array (RT² Profiler PCR Array PAHS-0120Z, SABiosciences) and analyzed using the provided RT Profiler PCR Array Data Analysis v. 3.5 software.

Gene symbol	Refseq	Description	Fold regulation
Profibrotic and inflammatory cytokines
ACTA2	NM_001613	Actin, alpha 2, smooth muscle, aorta	−1.8557
CCL2 (MCP1)	NM_002982	Chemokine (C-C motif) ligand 2	−4.2634
IL-1B	NM_000576	Interleukin 1, beta	−4.0615
Extracellular matrix, ECM remodeling and cell adhesion
COL1A2	NM_000089	Collagen, type I, alpha 2	−2.4318
MMP1	NM_002421	Matrix metallopeptidase 1 (interstitial collagenase)	−60.6317
MMP3	NM_002422	Matrix metallopeptidase 3 (stromelysin 1, progelatinase)	−5.0002
MMP9	NM_004994	Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase)	−1.948
TIMP1	NM_003254	TIMP metallopeptidase inhibitor 1	−2.0167
TIMP3	NM_000362	TIMP metallopeptidase inhibitor 3	−2.6427
PLAT	NM_000930	Plasminogen activator, tissue	−1.9079
PLAU	NM_002658	Plasminogen activator, urokinase	−3.6351
SERPINE1	NM_000602	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	−2.2377
ITGA2	NM_002203	Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	−4.8299
Signal transduction (TGFβ superfamily and transcription factors)
CEBPB	NM_005194	CCAAT/enhancer binding protein (C/EBP), beta	−1.9616
STAT1	NM_007315	Signal transducer and activator of transcription 1	−1.8557
TGFBR1	NM_004612	Transforming growth factor, beta receptor 1	−1.9752
TGFBR2	NM_003242	Transforming growth factor, beta receptor 2	−1.948
TGIF1	NM_003244	TGFB-induced factor homeobox 1	−2.0591
THBS1	NM_003246	Thrombospondin 1	3.1123
THBS2	NM_003247	Thrombospondin 2	−1.8947

Bold characters indicate genes upregulated or downregulated by ⩾1.8-fold.