Table II.

Pathway enrichment analysis of compound targets, uterine fibroids targets and compound targets/uterine fibroids targets.

Pathway	Gene count	%	P-value	Fold enrichment	Benjamini
Phosphoinositide 3-kinase/Akt signaling	56	0.086	9.10E-14	3.0	2.70E-12
Ras signaling	44	0.068	1.20E-13	3.6	3.30E-12
MAPK signaling	32	0.049	1.30E-5	2.3	6.80E-5
Estrogen signaling	25	0.038	2.30E-10	4.7	2.80E-9
Vascular endothelial growth factor signaling	22	0.034	2.10E-12	6.7	4.60E-11
Mechanistic target of rapamycin signaling	16	0.025	2.40E-7	5.1	1.60E-6
Wingless-type signaling	14	0.022	3.20E-2	1.9	7.10E-2
Apoptosis	12	0.018	3.90E-4	3.6	1.50E-3
Epidermal growth factor signaling	11	0.017	2.40E-4	3.8	4.50E-3
Insulin-like growth factor-1 signaling	10	0.015	1.30E-4	4.5	3.20E-3
Role of ErbB2 receptor tyrosine kinase 2 in signal transduction and oncology	10	0.015	3.10E-4	4.1	5.30E-3
Platelet-derived growth factor signaling	10	0.015	1.60E-3	3.3	1.70E-2
Transforming growth factor-β signaling	10	0.015	3.30E-2	2.2	7.20E-2
Nuclear factor-κB signaling	10	0.015	4.30E-2	2.1	9.00E-2
Extracellular signal-regulated kinase 1/2-MAPK signaling	8	0.012	3.30E-2	2.5	1.50E-1

Benjamini score was derived from the DAVID database. Percentage values were calculated from the associated genes/total genes.