Table III.

GO enrichment analysis of compound targets, uterine fibroids targets, compound targets/uterine fibroids targets and other human proteins.

GO ID	Pathway	Gene count	%	P-value	Fold enrichment	Benjamini
0007173	Epidermal growth factor receptor signaling	64	0.124	5.80E-44	9.7	5.60E-41
0008543	Fibroblast growth factor receptor signaling	60	0.117	4.60E-42	10.1	3.60E-39
0048010	Vascular endothelial growth factor receptor signaling	53	0.103	4.90E-35	9.3	2.40E-32
0048009	Insulin-like growth factor receptor signaling	4	0.008	2.60E-3	14.0	3.00E-2
0007179	Transforming growth factor-β receptor signaling	30	0.058	8.60E-22	10.9	1.70E-19
0030512	Negative regulation of transforming growth factor-β receptor signaling	11	0.021	2.70E-6	7.2	6.10E-5
0032355	Response to estradiol	22	0.043	2.40E-14	9.2	2.10E-12
0043627	Response to estrogen	13	0.025	6.10E-9	9.8	2.20E-7
0043401	Steroid hormone-mediated signaling	12	0.023	2.40E-8	10.0	7.60E-7
0008285	Negative regulation of cell proliferation	37	0.072	5.20E-14	4.6	3.90E-12
0048662	Negative regulation of smooth muscle cell proliferation	6	0.012	5.00E-4	8.9	6.90E-3
0097190	Apoptotic signaling	10	0.019	7.60E-4	4.1	1.00E-2
0043065	Positive regulation of apoptotic processes	34	0.066	2.10E-15	5.6	2.20E-13

Benjamini score was derived from the DAVID database. Percentage values were calculated from the associated genes/total genes.