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. 2017 Sep 19;14(5):4817–4824. doi: 10.3892/etm.2017.5142

Table I.

Immunohistochemical staining for IDO and SOCS3 in chorionic villi and decidua from normal pregnancies.

Y (Intensity of IDO immunostaining)

X (intensity of SOCS3 immunostaining) + ++ +++ ++++ Total
+ 2 5 5 1 13
++ 5 6 0 0 11
Total 7 11 5 1 24
Linear-By-linear association 6.031
Asymp. Sig. (2-sided) 0.014
Spearman's correlation −0.511
Approx. Sig. 0.011

The results from linear-by-linear association are 6.031, which shows that there is a linear trend between IDO and SOCS3. The correlation coefficient calculated by Spearman's correlation is −0.511 (P=0.011), further explaining that they are negatively correlated.