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. 2017 Sep 19;14(5):4817–4824. doi: 10.3892/etm.2017.5142

Table II.

Immunohistochemical staining for IDO and TGF-β in chorionic villi and decidua from normal pregnancies.

Y(Intensity of IDO immunostaining)

X (intensity of TGF-β immunostaining) + ++ +++ Total
2 0 0 2
+ 1 5 0 6
++ 2 10 2 14
+++ 0 1 1 2
Total 5 16 3 24
Linear-By-linear association 6.264
Asymp.Sig (2-sided) 0.012
Spearman's correlation 0.474
Approx. Sig. 0.019

The results from linear-by-linear association are 6.264, which shows that there is a linear trend between IDO and TGF-β. The correlation coefficient calculated by Spearman's correlation is 0.474 (P=0.019), further explaining that they are negatively correlated.