Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 19;14(5):4919–4927. doi: 10.3892/etm.2017.5127

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Cao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 5. — Neuroprotective effect of LBP in rats against CoCl₂. Rats were treated with CoCl₂ and subsequently received intraperitoneal LBP (100 mg/kg) or saline solution with or without ZnPP (10 mg/kg). The expression of (A) Nrf2 and (B) HO-1 mRNA in brain tissue was determined by reverse transcription-quantitative polymerase chain reaction and the results are presented as folds of the control. (C) Apoptosis was determined by TUNEL staining and results were shown as folds of the control. (D) A MWM test was conducted to evaluate spatial learning and memory abilities of rats. Development of spatial memory for platform location during the probe trials following 5 days training during the MWM test. The crossing index represents the average frequency of swims over the platform site in the target quadrant. (E) Average escape latencies. (F) The distance traveled to find the platform. *P<0.05 vs. control; ^#P<0.05 vs. H₂O₂ treatment; ^P<0.05 vs. LBP treatment. Nrf2, nuclear factor erythroid 2-related factor 2; HO-1, heme oxygenase-1; ZnPP, zinc protoporphyrin IX; MWM, morris water maze; LBP, Lycium barbarum polysaccharide.