Table II.
Top 10 significantly upregulated and downregulated DEGs identified in multiple myeloma. All gene ID's were taken from the Entrez database on NCBI.
| A, Upregulated DEGs | |||
|---|---|---|---|
| Entrez gene ID | Abbreviation | Name | FDR |
| 84265 | POLR3GL | Polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like | 0.0001793 |
| 8364 | HIST1H4C | Histone cluster 1, H4c | 0.0002646 |
| 6170 | RPL39 | Ribosomal protein L39 | 0.0013368 |
| 5880 | RAC2 | Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.0013368 |
| 29080 | CCDC59 | Coiled-coil domain containing 59 | 0.0013368 |
| 521 | ATP5I | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E | 0.0013773 |
| 9991 | PTBP3 | Polypyrimidine tract binding protein 3 | 0.001458 |
| 79023 | NUP37 | Nucleoporin 37kDa | 0.001458 |
| 64801 | ARV1 | ARV1 homolog, fatty acid homeostasis modulator | 0.001458 |
| 3700 | ITIH4 | Inter-α-trypsin inhibitor heavy chain family, member 4 | 0.001458 |
| B, Downregulated DEGs | |||
| Entrez gene ID | Abbreviation | Name | FDR |
| 387 | RHOA | Ras homolog family member A | 0.0004738 |
| 23256 | SCFD1 | Sec1 family domain containing 1 | 0.0013368 |
| 92241 | RCSD1 | RCSD domain containing 1 | 0.0014580 |
| 126364 | LRRC25 | Leucine rich repeat containing 25 | 0.0017804 |
| 5226 | PGD | Phosphogluconate dehydrogenase | 0.0026507 |
| 129531 | MITD1 | MIT, microtubule interacting and transport, domain containing 1 | 0.0027447 |
| 10023 | FRAT1 | Frequently rearranged in advanced T-cell lymphomas 1 | 0.0027447 |
| 8883 | NAE1 | NEDD8 activating enzyme E1 subunit 1 | 0.0028332 |
| 81631 | MAP1LC3B | Microtubule-associated protein 1 light chain 3 β | 0.0028998 |
| 4904 | YBX1 | Y box binding protein 1 | 0.0028998 |
DEGs, differentially expressed genes; FDR, false discovery rate. Entrez database: https://www.ncbi.nlm.nih.gov/gene.