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. 2017 Nov 28;22:24. doi: 10.1186/s11658-017-0056-y

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Immunohistochemical analysis of HSP27 in the aortic samples of both controls and patients. a – HSP27 expression was higher in the aortic media of patients with TAD than in that of controls. HSP27-negative bands are observed along the tear in the aortic media of patients with TAD. * indicates false lumen. Scale bar = 100 μm. b – Double immunofluorescence staining showing colocalization of HSP27 and SM22α in the aortic media of TAD patients. Scale bar = 100 μm