Table 5.

Prognostic variables tested using univariate Cox proportional-hazard analysis.

	≤2 cm (n = 59)		All tumours (n = 193)
	PFS		PFS		All-cause mortality
	HR	P	HR	P	HR	P
Age	1.020	0.426	1.005	0.546	1.038	0.006*
Female gender	0.381	0.012*	0.584	0.01*	0.893	0.701
Resection > 2010	0.629	0.167	0.727	0.185	0.421	0.015*
Diameter	1.121	0.111	1.012	<0.001*	1.005	0.268
Benign features	0.723	0.231	0.327	<0.001*	0.733	0.404
Vascular invasion	2.095	0.213	2.097	0.001**		ns
N1	2.87	0.051	1.669	0.02*	1.447	0.234
LNR <0.2 vs >0.2		ns	0.816	0.686	0.565	0.141
Metastasis	2.968	0.072	2.991	<0.001***	2.198	0.009*
Extrahepatic	10.797	0.001**	0.378	0.001**	4.231	<0.001***
Stage vs IV
I	0.255	0.045*	0.176	<0.001***	0.425	0.087
II	0.901	0.906	0.348	<0.001***	0.562	0.135
III	0.396	0.234	0.407	<0.001***	0.402	0.018*
Grade vs G3
G1	0.329	0.04*	0.276	<0.001***	0.121	<0.001***
G2	No G3		0.568	0.068	0.274	<0.001***
R1/R2 Margin	1.382	0.678	2.312	0.001**	1.104	0.803

*P < 0.05; **P < 0.005; ***P < 0.001.

HR, hazard ratio; LNR, lymph node ratio; PFS, progression-free survival.