Gene-regulatory regions in corneal epithelial cells are related to those in other epithelial cell types.
A, clustering of primary cell types based on similarities in TEs (left panel) and SEs (right panel). B, overlap between SEs in primary epithelial cell types. C, assessment of the regulatory cell state of HCE SE regions in other epithelial cells (HMEC and NHEK), mesodermally derived cells (NHLF), and hESCs. D, GO for genes linked to cornea-specific TEs. E, enriched GO for epidermis-specific TEs. F, enriched GO for mammary epithelium–specific TEs. G, GO for genes linked to cornea-specific SEs. H, enriched GO for epidermis-specific SEs. I, enriched GO for mammary epithelium-specific SEs.