Table 3.

Rosetta energy calculations for five steric zipper segments identified in the prion protein

The position of the N or Q residue is shown as bold text.

Asn/Gln position	Zipper segments identified by ZipperDB	Rosetta energy
		kcal/mol
100	QWNKPSK	−29.2
143	MIHGNDW	−26
168	QYNNQNN	−34.6
174	QYNNQNN	−34.6
219	QYQKESQ	−31.2