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. 2017 Nov 28;17:130. doi: 10.1186/s12876-017-0688-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effect of oral administration of vitamin D-enriched mushrooms on the immune system. Serum levels of TNF_α, IL-1_α, IL-1_β, TGF_β, IL-6 and IL-10 were measured by ELISA at the end of the study (a-f). FACS analysis was performed on lymphocytes isolated from spleens. Effect of treatment on the CD4/CD8 lymphocyte ratio (g). Data represent mean +/− SE from N = 4–6 mice per group. p value (by Kruskal-Wallis test) < 0.05 for TNF_α, IL-1_α, IL-1_β and IL-6. * - p value <0.05 (by Mann-Whitney test)