Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 28;18:339. doi: 10.1186/s12882-017-0756-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — Representative findings of tubulointerstitial changes in MCNS patients. a-f Vacuoles (a, arrow heads), hyaline droplets (b, arrow heads) and proteinaceous casts (b, asterisks) are observed in tubules. Tubular simplification, including loss of brush-border of the proximal tubule (b, arrow) and dilated tubule with flattening of tubular epithelium, is also observed. c Tubular necrosis is focally observed in a patient in the AKI group (asterisk). d Severe interstitial edema due to the expansion of intertubular spaces and dilated peritubular capillaries with tubular collapses is noted. H & E staining (e) and Masson’s trichrome staining (f) in consecutive sections. Tubules with tubular simplification (e) are situated on the thin tubular basement membrane that appears to be normal and is not surrounded by an accumulation of collagen fibres, as assessed by Masson’s trichrome-positivity (g: glomeruli; a-d, PAS staining; original magnification ×200).