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Predicted inhibition percentage of COX-1 and COX-2 for the observed robenacoxib concentrations at 1 and 5 h; mean (SD) [max], N = 80
| Time | Group 2 | Group 3 | Group 4 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| % inhibition COX-1 | 1 | 24 | (9) | [50] | 23 | (10) | [44] | 29 | (11) | [53] |
| % inhibition COX-1 | 5 | 6 | (5) | [22] | 10 | (8) | [30] | 11 | (10) | [36] |
| % inhibition COX-2 | 1 | 82 | (23) | [99] | 79 | (27) | [98] | 87 | (20) | [99] |
| % inhibition COX-2 | 5 | 24 | (27) | [88] | 39 | (32) | [95] | 41 | (32) | [97] |
