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. 2016 Oct 3;58(10):979–986. doi: 10.1097/JOM.0000000000000841

TABLE 3.

Mixed-Level Logistic Regression Analysis of Average Ambient Air Pollutants and Cord Blood Immune System Biomarkers Among Girls, Odds Ratios, and 95% Confidence Intervals (n = 507)

Pollutant IgE ≥0.5 ku/L IL-33 ≥80%ile TSLP ≥80%ile IL-33/TSLP ≥80%ile
NO2, ppb
 ≤7.77 1.0 1.0 1.0 1.0
 7.78 to ≤14.15 1.28 (0.63–2.61) 2.31 (1.14–4.65) 2.25 (1.16–4.38) 1.91 (0.86–4.21)
 14.16 to ≤20.76 1.93 (0.93–3.99) 2.51 (1.19–5.28) 2.87 (1.43–5.76) 2.77 (1.24–6.20)
 >20.76 1.02 (0.47–2.17) 3.20 (1.60–6.40) 3.00 (1.55–5.82) 3.42 (1.61–7.27)
 1 1.01 (0.98–1.04) 1.04 (1.04–1.08) 1.04 (1.01–1.07) 1.05 (1.02–1.08)
PM2.5, μg/m3
 ≤6.01 1.0 1.0 1.0 1.0
 6.02 to ≤8.43 1.97 (0.93–4.20) 1.26 (0.61–2.60) 1.52 (0.78–2.97) 1.35 (0.64–2.82)
 8.44 to ≤9.23 1.37 (0.64–2.92) 1.53 (0.79–2.98) 1.44 (0.75–2.78) 1.44 (0.70–2.95)
 >9.23 2.57 (1.24–5.32) 1.25 (0.57–2.70) 1.14 (0.55–2.37) 1.04 (0.47–2.31)
 1 1.14 (1.00–1.31) 1.07 (0.93–1.23) 1.03 (0.89–1.18) 1.02 (0.88–1.18)

IgE, immunoglobulin E; IL, interleukin; TSLP, thymic stromal lymphopoietin.

*Adjusted for maternal age, household income (center and FSA are random effects).

Pollutant concentrations are average exposure levels throughout pregnancy.