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. 2017 Nov 28;4:170173. doi: 10.1038/sdata.2017.173

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Copyright © 2017, The Author(s)

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files made available in this article.

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(a) Percentage of mapped reads at promoters identified by DPI for each sample. Labels description: AoSMC=aortic smooth muscle cell; AoSMCdiff=differentiated aortic smooth muscle cell; MESbm=mesenchymal stem cell from bone marrow; Hep=hepatocyte; UniTis=Universal tissue; (b) histograms of CAGE peaks lengths; (c) enrichment of TATA motifs near CAGE peaks; (d) graphs showing TATA-rich versus CpG-rich peaks. TATA-only bound CAGE peaks tend to be sharp whereas CpG-only peaks are generally broader; (e) percentage of genes that can be associated to a CAGE peak for each of the inspected known models; (f) distribution of the distances of CAGE peaks from their closest gene TSS. Colours: orange denotes rat and blue dog, except for (d), where colour-code is specified in the legend.