Table 3.

Patient-based diagnostic performance of Gd-EOB-DTPA-enhanced MRI and dynamic MDCT for recurrence of hypervascular HCC in 97 patients

	Gd-EOB-DTPA-enhanced MRI			Dynamic MDCT			p value
		patients, n	95% CI		patients, n	95% CI
Observer 1
AUROC	0.95		0.91–0.99	0.76		0.67–0.84	<0.001a
Sensitivity	0.88	42/48	0.78–0.97	0.52	25/48	0.37–0.67	<0.001b
Specificity	0.94	46/49	0.87–1.01	0.92	45/49	0.84–1.00	1b
Accuracy	0.91	88/97	0.85–0.97	0.72	70/97	0.63–0.81	0.002b
PPV	0.93	42/45	0.86–1.01	0.86	25/29	0.73–1.00	0.27c
NPV	0.88	46/52	0.79–0.97	0.66	45/68	0.55–0.78	0.004c
Observer 2
AUROC	0.90		0.84–0.96	0.74		0.66–0.83	0.002a
Sensitivity	0.83	40/48	0.72–0.94	0.52	25/48	0.37–0.67	<0.001b
Specificity	0.94	46/49	0.87–1.01	0.92	45/49	0.84–1.00	1b
Accuracy	0.89	86/97	0.82–0.95	0.72	70/97	0.63–0.81	0.004b
PPV	0.93	40/43	0.85–1.01	0.86	25/29	0.73–1.00	0.29c
NPV	0.85	46/54	0.75–0.95	0.66	45/68	0.55–0.78	0.013c

AUROC, area under the receiver operating characteristic curve; PPV, positive predictive value; NPV, negative predictive value.

^aUnivariate z score test.

^bMcNemar test.

^cFisher's exact probability test.