Figure 3.

Adjusted hazard ratios (HRs) for cardiovascular disease mortality per year increase in age at menopause, within various subgroups, among postmenopausal women only. Models were stratified by age and study area and adjusted for education, household income, smoking, alcohol drinking, blood pressure, body mass index, physical activity, prior diabetes mellitus status, age at menarche, parity, abortion, age at first birth, breastfeeding duration per child, and oral contraceptive use. The dotted vertical line indicates the overall change of every 1 y greater age at menarche; the open diamond indicates this estimate and its 95% confidence interval (CI). Sensitivity analyses were among (1) women who never smoked, drank alcohol, or used oral contraceptives and (2) women who were aged >57 y at enrollment.