Figure 2.

a) Mechanochemical reactivity between the excipient MgO and carboxylic acid NSAID molecules; b) NSAID molecules explored in mechanochemical reactions with MgO; c) fragment of the crystal structure of a mechanochemically obtained magnesium–ibuprofen complex; d) fragment of the crystal structure of a mechanochemically obtained magnesium–salicylate complex; e) screening for different hydrated forms of magnesium–naproxen BioMOFs by systematically varying the quantity of water in LAG reactions of MgO and (S)-naproxen. Reprinted with permission from [29], copyright 2012 the Royal Society of Chemistry.