Table 2.

Loci Achieving Genome-Wide Significance (P<5.0×10⁻⁸) for Any Long Term Average Blood Pressure Phenotype in Meta-Analysis.

SNP	Chr	Position (Build 36)	CA	CAF	Nearest Gene	Study	Beta, mm Hg	SE	P
LTA Systolic Blood Pressure
rs4919669	10	104461965	A	0.43	ARL3	AGEN	−0.96	0.18	5.03E-08
						CHARGE	−0.41	0.15	8.64E-03
						Meta	−0.65	0.12	2.63E-08
rs284844	10	104544519	A	0.49	WBP1L	AGEN	−0.99	0.17	4.61E-09
						CHARGE	−0.57	0.15	8.75E-05
						Meta	−0.75	0.11	1.05E-11
rs11191580	10	104896201	T	0.74	NT5C2	AGEN	1.18	0.20	1.83E-09
						CHARGE	0.83	0.16	1.78E-07
						Meta	0.97	0.12	4.44E-15
rs12579302	12	88574634	A	0.65	ATP2B1	AGEN	0.96	0.19	2.50E-07
						CHARGE	0.93	0.12	5.08E-15
						Meta	0.94	0.10	<1E-17
LTA Diastolic Blood Pressure
rs284844	10	104544519	A	0.49	WBP1L	AGEN	−0.53	0.10	7.14E-08
						CHARGE	−0.23	0.09	5.81E-03
						Meta	−0.36	0.06	2.05E-08
rs4409766	10	104606653	T	0.72	C10orf32	AGEN	0.55	0.11	4.13E-07
					-AS3MT	CHARGE	0.30	0.09	8.42E-04
						Meta	0.40	0.07	7.43E-09
rs11105364	12	88593407	T	0.65	ATP2B1	AGEN	0.58	0.11	1.08E-07
						CHARGE	0.53	0.07	7.29E-14
						Meta	0.54	0.06	<1E-17
LTA Mean Arterial Pressure
rs4919669	10	104461965	A	0.43	ARL3	AGEN	−0.72	0.12	3.59E-09
						CHARGE	−0.24	0.10	2.35E-02
						Meta	−0.44	0.08	2.64E-08
rs284844	10	104544519	A	0.49	WBP1L	AGEN	−0.70	0.12	1.15E-09
						CHARGE	−0.34	0.10	5.23E-04
						Meta	−0.49	0.07	4.66E-11
rs4409766	10	104606653	T	0.72	C10orf32	AGEN	0.74	0.13	6.87E-09
					-AS3MT	CHARGE	0.42	0.10	4.38E-05
						Meta	0.54	0.08	9.90E-12
rs12579302	12	88574634	A	0.66	ATP2B1	AGEN	0.68	0.13	7.27E-08
						CHARGE	0.68	0.08	3.43E-17
						Meta	0.68	0.07	<1E-17

CA=Coded allele; CAF=Coded allele frequency; LTA=Long term average; SE=standard error; SNP=single nucleotide polymorphism;