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. Author manuscript; available in PMC: 2018 Jul 18.
Published in final edited form as: Biochemistry. 2017 Jul 3;56(28):3669–3681. doi: 10.1021/acs.biochem.7b00359

Table 1.

Kd values ± standard deviations for apoCaM binding to IQ domain – derived peptides

WT K1647A F1648A Y1649A I1654A Q1655A
Kd (μM) 40.5±14.3 44.2±21.8 32.4±3.8 61.9±21.8 141.2±29.5*** 22.3±1.3

Significant differences to WT means were only found for I1654A (***, p<0.001; ANOVA followed by Tukey and Bonferroni post hoc test; N=3–6).