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. Author manuscript; available in PMC: 2018 Dec 1.

Published in final edited form as: Free Radic Biol Med. 2017 Oct 6;113:280–290. doi: 10.1016/j.freeradbiomed.2017.10.004

Table 2. Impact of fNASH and nfNASH on expression of thioredoxin and antioxidant responses.

Quantitative analysis of Western blots presented in Figure 4A.

Normal fNASH	Thioredoxin signaling			Antioxidant response
	Trx1	TrxR1	TxNIP	GSTπ	SOD2	catalase

	100±10.85	100±7.20	100±28.56	100±30.72	100±21.21	100±4.66

	183.74±16.60^a	88.31±8.97	375.33±61.25^a	7260.08±2157.12^a	217.42±15.09^a	82.09±4.67^a

Normal nfNASH	Trx1	TrxR1	TxNIP	GSTπ	SOD2	catalase

	100±18.25	100±12.74	100±24.11	100±53.93	100±23.63	100±4.85

	128.57±24.19	84.38±11.28	1407.73±490.01^a	1996.23±336.93^a	216.58±26.29^a	77.03±5.16^a

Each band was quantified using NIH ImageJ and normalized against total GADPH expression. N=6 normal, 6=fNASH, 6=nfNASH, data are means +/− SEM,

^a

= statistically significant change when compared to expression in normal tissue.