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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2017 Oct 6;113:280–290. doi: 10.1016/j.freeradbiomed.2017.10.004

Table 3. Impact of fNASH and nfNASH on expression of enzymes regulating protein folding.

Quantitative analysis of Western blots presented in Figure 7.

Normal fNASH Protein folding Heat shock Response
Grp94 Hsp70 Grp78 Chop Vimentin
100±24.82 100±4.75 100±7.01 100±49.08 100±45.30
70.36±20.65 39.39±4.63a 85.59±6.93 212.07±72.07 2696.27±588.96a
Normal nfNASH Grp94 Hsp70 Grp78 Chop Vimentin
100±18.25 100±9.12 100±6.33 100±18.32 100±54.64
77.05±28.02 54.06±4.48a 91.11±7.42 31.61±6.43a 5528.46±3834.77a

Each band was quantified using NIH ImageJ and normalized against total GADPH expression. N=6 normal, 6 fNASH, 6 nfNASH, data are means +/− SEM,

a

= statistically significant change when compared to expression in normal tissue.