Table 6.

Heart Rate Response to Mental Stress: Cox Proportional Regression Analyses for Death or Cardiac Hospitalization.

Variable	Planned Model* HR (95% CI)	P Value	Extended Model† HR (95% CI)	P Value
Etiology	1.783 (1.286 – 2.472)	0.001	1.780 (1.281 – 2.474)	0.001
LVEF/10	0.809 (0.691 – 0.947)	0.009	0.797 (0.677 – 0.938)	0.006
ProBNP/1000	1.065 (1.015 – 1.117)	0.010	1.077 (1.025 – 1.131)	0.003
Baseline Heart Rate/10	1.266 (1.086 – 1.476)	0.003	1.233 (1.058 – 1.437)	0.007
Heart Rate Reactivity/10	0.813 (0.613 – 1.078)	0.150	0.816 (0.614 – 1.085)	0.162
Depression	-	-	1.033 (1.010 – 1.055)	0.004

HR = Hazard ratio; CI = confidence Interval; LVEF = left ventricular ejection fraction; BNP = Brain Natriuretic Peptide.

^*Adjusted for etiology, LVEF, ProBNP, baseline heart rate and heart rate reactivity to stress task.

^†Adjusted for the variables in the a priori planned model, as well as depression score.