Table 1.
Logistic regression model p-values for prognostic factors for Gleason upgrading. Univariate (UV) p-values are from single variable models. Multivariate (MV) p-values are from the final model selected from a stepwise selection procedure.
| NCCN Cohorts* | ||||
|---|---|---|---|---|
| 2012 (N=224, Yes=99, No=125) | 2014 (N=206, Yes=94, No=112) | |||
| Variable | UV | MV | UV | MV |
| Pretreatment Gleason Score | ||||
| Ethnicity | .0598 | .0460* | .0702 | .0395* |
| Race | .2404 | .4513 | ||
| Age | .1590 | .0080* | .0066* | |
| DRE | .1026 | .1462 | ||
| T Stage | .0860 | .0934 | ||
| Prebiopsy Serum PSA | .0001** | <.0001** | .0002** | <.0001** |
| PCA3 RNA | .6811 | .7230 | ||
| PCA3 RNA/ Input RNA | .6914 | .7215 | ||
| PCA3 RNA/PSA mRNA | .1946 | .1906 | ||
| TMPRSS2:ERG | .5614 | .5773 | ||
| TMPRSS2:ERG/Input RNA | .5888 | .5956 | ||
| TMPRSS2:ERG/PSA mRNA | .5188 | .5385 | ||
| PSA_mRNA | .2326 | .2563 | ||
| PSA mRNA/Input RNA | .2356 | .2320 | ||
| Expressed Volume Prostatic Fluid (μL) | .7702 | .5221 | ||
| Total RNA in specimen (ng) | .5982 | .5917 | ||