Table 1.
The connexin protein and gene families in humans and mice.
| Human | Mouse | |||
|---|---|---|---|---|
|
|
|
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| Gene symbol |
Protein name |
Synonyms | Gene symbol |
Protein name |
| GJB1 | CX32 | CMTX1, CMTX | Gjb1 | Cx32 |
| GJB2 | CX26 | DFNB1, DFNA3, NSRD1 | Gjb2 | Cx26 |
| GJB3 | CX31 | DFNA2, EKV | Gjb3 | Cx31 |
| GJB4 | CX30.3 | Gjb4 | Cx30.3 | |
| GJB5 | CX31.1 | Gjb5 | Cx31.1 | |
| GJB6 | CX30 | DFNA3, ED2, EDH, HED | Gjb6 | Cx30 |
| GJB7 | CX25 | – | – | |
| GJA1 | CX43 | ODDD, ODOD, SDTY3 | Gja1 | Cx43 |
| GJA3 | CX46 | CZP3 | Gja3 | Cx46 |
| GJA4 | CX37 | Gja4 | Cx37 | |
| GJA5 | CX40 | Gja5 | Cx40 | |
| – | – | Gja6 | Cx33 | |
| GJA8 | CX50 | CAE1, CZP1, CAE | Gja8 | Cx50 |
| GJA9 | CX59 | – | – | |
| GJA10 | CX62 | Gja10 | Cx57 | |
| GJC1 | CX45 | Gjc1 | Cx45 | |
| GJC2 | CX47 | SPG44 | Gjc2 | Cx47 |
| GJC3 | CX30.2/31.3 | Gjc3 | Cx29 | |
| GJD2 | CX36 | Gjd2 | Cx36 | |
| GJD3 | CX31.9 | Gjd3 | Cx30.2 | |
| GJD4 | CX40.1 | Gjd4 | Cx39 | |
| Gje1 | Cx23 | |||
Modified from Beyer and Berthoud [8] and from http://www.genenames.org/genefamilies/GJ. Cx has been generally used as an abbreviation for Connexin. Many of the synonyms refer to genetic diseases or syndromes linked to mutations of the connexins.