Table 2.

Univariate and Multivariate Analysis of DMFS

	Univariate		Multivariate
	P-Value	HR (95% CI)	P-Value	HR (95% CI)
Age >65 vs ≤65	0.37	0.79 (0.49–1.31)	–	–
T-stage	<0.001	2.27 (1.74–2.99)	<0.001	1.72 (1.27–2.32)
Gleason score	<0.001	3.17 (2.19–4.61)	<0.001	2.661 (1.69–4.18)
PSA	0.052	1.61 (1.00–2.61)	0.49	1.25 (0.66–2.39)
ADT (yes vs no)	0.03	1.842 (1.061–3.20)	0.054	0.51 (0.26–1.01)
% Core Positivity (>50% vs ≤50%)	<0.0001	4.24 (2.57–6.99)	0.001	2.55 (1.50–4.32)
PSA density (>0.25 vs ≤0.25)	0.003	2.07 (1.27–3.36)	0.42	1.31 (0.69–2.48)

Abbreviations: ADT, androgen-deprivation therapy; CI, confidence interval; HR, hazard ration; PSA, prostate-specific antigen