FIG. 8.

Comparison of survivin-mediated radio-adaptive survival responses in cultures of HCT116 TP53 WT and RKO TP53 WT cells irradiated in conditioned medium obtained from their corresponding isogenic TP53 null cell cultures, and HCT116 isogenic TP53 null and RKO isogenic TP53 null cells irradiated in conditioned medium obtained from their corresponding TP53 WT cell cultures. P values were determined by comparing the survival of cells after exposure to two 2 Gy doses with those exposed to two 2 Gy doses along with the 5 mGy doses. Each experiment was repeated three times and error bars represent SEM.