Figure 4. Inhibition of CMV replication by the VDR agonist EB-1089.
100 % confluent HFF were seeded in 24-wells, infected with CMV strain AD169 and treated with 1 nM Calcitriol and two-fold dilution series of EB-1089 or Ganciclovir starting with 200 nM or 200 µM, respectively. All experiments were done in triplicates (arrow bars show SEM). The dashed line indicates 50 % inhibition of CMV replication.