Table 1. Inflammatory cells in lungs of Dp-CE allergic mice compared with normal and sham mice before vaccination (BV) and after vaccination/placebo and provocation with Dp-CE (PP).
Group | Mean ± SD of cells/microscopic field* | ||||
---|---|---|---|---|---|
Neutrophil | Lymphocyte | Eosinophil | Macrophage | Total cells | |
Before vaccination (BV) | |||||
Normal | 4.46 ± 3.32 a | 3.05 ± 6.57a | 0 | 0.188 ± 1.68a | 7.70 ± 7.47a |
Sham | 37.28 ± 25.83b | 9.275 ± 5.70b | 0 | 0 | 46.55 ± 26.27b |
Allergenized mice | 88.66 ± 43.47 c | 125.44 ± 71.89c | 1.15 ± 2.27 a | 0 | 215.25 ± 90.85c |
After vaccination and provocation (PP) | |||||
Sham | 31.76 ± 22.90b | 11.41 ± 14.01b | 0 | 0 | 43.18 ± 35.02b |
L-CE | 119.33 ± 56.17c | 61.44 ± 64.87d | 0.96 ± 1.69a | 0.10 ± 0.27a | 181.84 ± 89.86d |
L- Der p 1 | 48.73 ± 36.99d | 37.79 ± 37.75e | 0.24 ± 0.75b | 0.05 ± 0.30a | 86.81 ± 64.31e |
L-Der p 2 | 55.42 ± 12.70e | 36.36 ± 8.47e | 0.45 ± 0.81c | 0 | 92.23 ± 24.47e |
L-Com | 46.31 ± 26.35d | 35.76 ± 34.16e | 0.25 ± 0.91b | 0.05 ± 0.29a | 82.37 ± 47.74e |
L-PBS | 68.54 ± 44.31c,e | 41.91 ± 53.89e | 0.20 ± 1.02b | 0.04 ± 0.28a | 110.69 ± 87.30f |
*, Average of at least 20 microscopic fields (10 × 40) per mouse
Entries with different superscripts (a, b, c, d, e and f) of the same column are statistically different (p <0.05)