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. 2017 Nov 28;12(11):e0188196. doi: 10.1371/journal.pone.0188196

Fig 1. Overview.

Fig 1

(A) Main steps of the analysis. (B) Using random splits of a dataset with replicate scans to check for disease (group) heterogeneity: (right) by placing different subjects (with all their replicate scans) in the two splits (“split subjects”) and respectively (left) by splitting the replicates of the same subjects in the two splits (“split replicates”). (a,b,c,… correspond to subjects, while, for instance, a’ and a” are replicate scans for subject a).