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. 2017 Nov 28;12(11):e0188342. doi: 10.1371/journal.pone.0188342

Fig 5. Ex vivo IFN-γ responses by ELISPOT assay during chikungunya.

Fig 5

PBMCs from 12 chronic patients, 12 individuals recovered from chikungunya, and 18 controls were assessed using IFN-γ ELISPOT assay. Box plots show (A) IFN-γ production in negative controls (PBMCs stimulated with medium only) (B) CHIKV specific IFN-γ production (after subtraction of spots in unstimulated PBMCs well from stimulated well) and (C) IFN-γ production in positive controls (PBMCs stimulated with Phytohemagglutinin A [PHA]). Nonparametric Kolmogorov-Smirnov-test was used for intergroup comparison. p value <0.05 is considered significant.