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. Author manuscript; available in PMC: 2018 Mar 14.
Published in final edited form as: Biochemistry. 2017 Mar 1;56(10):1482–1497. doi: 10.1021/acs.biochem.7b00016

Figure 10.

Figure 10

(a) Free energy profile along the MFEP obtained from the S236 mechanism in the PR state. Each dot corresponds to an image along the string. (b) Transition structure in which proton transfers between W1 and S236, and S236 and γ-phosphate.