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. 2017 Nov 7;6:e29830. doi: 10.7554/eLife.29830

Figure 5. HA biosynthesis is required for eIF4E-mediated lung metastasis in mice.

Figure 5.

(A) Histochemical staining of HA using biotinylated HABP in metastatic mouse tumors. +HAse indicates sections were treated with HAse prior to biotinylated HABP to ensure HA staining was specific. Red arrows indicate tumors. 3X (first and third row) and 50X (second row) magnification are presented. (B) Quantification from Visiomorph for all 19 mice over multiple sections per animal. For bar graphs, the mean ± standard deviation are shown. *p < 0.05 (Student’s t-test).